Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuropathological and biochemical criteria to identify acquired Creutzfeldt-Jakob disease among presumed sporadic cases.

Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Jun 2016

Kobayashi Atsushi, Parchi Piero, Yamada Masahito, Mohri Shirou, Kitamoto Tetsuyuki

Abstract excerpt

As an experimental model of acquired Creutzfeldt-Jakob disease (CJD), we performed transmission studies of sporadic CJD using knock-in mice expressing human prion protein (PrP). In this model, the inoculation of the sporadic CJD strain V2 into animals homozygous for methionine at polymorphic codon 129 (129 M/M) of the PRNP gene produced quite distinctive neuropathological and biochemical features, that is,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon
Share to Creutzfeldt-Jakob Syndrome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Knock-In Techniques

Share to Methionine

Share to Mice, Transgenic

Share to Prion Proteins

Share to PrPC Proteins

Share to PrPSc Proteins

Source

Identifiers

PMID: 26669818
DOI: 10.1111/neup.12270

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuropathological and biochemical criteria to identify acquired Creutzfeldt-Jakob disease among presumed sporadic cases.PMID 26669818Read ↗

Deciphering the pathogenesis of sporadic Creutzfeldt-Jakob disease with codon 129 M/V and type 2 abnormal prion protein.Semantic proximity Read ↗

A novel subtype of sporadic Creutzfeldt-Jakob disease with PRNP codon 129MM genotype and PrP plaques.Semantic proximity Read ↗

Sporadic Creutzfeldt-Jakob Disease MM1+2C and MM1 are Identical in Transmission Properties.Semantic proximity Read ↗

Sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

A novel phenotype of sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification.Semantic proximity Read ↗

Dura mater graft-associated Creutzfeldt-Jakob disease in Japan: clinicopathological and molecular characterization of the two distinct subtypes.Semantic proximity Read ↗

Molecular classification of sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Defining the phenotypic spectrum of sporadic Creutzfeldt-Jakob disease MV2K: the kuru plaque type.Semantic proximity Read ↗

Infectious and Sporadic Prion Diseases.Semantic proximity Read ↗

Distinct pathological phenotypes of Creutzfeldt-Jakob disease in recipients of prion-contaminated growth hormone.Semantic proximity Read ↗

Cross-sequence transmission of sporadic Creutzfeldt-Jakob disease creates a new prion strain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.