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Article

Distinct pathological phenotypes of Creutzfeldt-Jakob disease in recipients of prion-contaminated growth hormone.

Acta neuropathologica communications - 25 Jun 2015

Cali Ignazio, Miller Cathleen J, Parisi Joseph E, Geschwind Michael D, Gambetti Pierluigi, Schonberger Lawrence B

Abstract excerpt

INTRODUCTION: The present study compares the clinical, pathological and molecular features of a United States (US) case of growth hormone (GH)-associated Creutzfeldt-Jakob disease (GH-CJD) (index case) to those of two earlier referred US cases of GH-CJD and one case of dura mater (d)-associated CJD (dCJD). All iatrogenic CJD (iCJD) subjects were methionine (M) homozygous at codon 129 (129MM) of the prion protein...

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Identifiers

PMID: 26108478
DOI: 10.1186/s40478-015-0214-2
PMCID: PMC4479081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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