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Article

Genetic structure of the Newfoundland and Labrador population: founder effects modulate variability.

European journal of human genetics : EJHG - 1 Jul 2016

Zhai Guangju, Zhou Jiayi, Woods Michael O, Green Jane S, Parfrey Patrick, Rahman Proton, Green Roger C

Abstract excerpt

The population of the province of Newfoundland and Labrador (NL) has been a resource for genetic studies because of its historical isolation and increased prevalence of several monogenic disorders. Controversy remains regarding the genetic substructure and the extent of genetic homogeneity, which have implications for disease gene mapping. Population substructure has been reported from other isolated populations...

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Identifiers

PMID: 26669659
DOI: 10.1038/ejhg.2015.256
PMCID: PMC5070906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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