Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Newfoundland population: a unique resource for genetic investigation of complex diseases

5 Aug 2003

Abstract excerpt

The population of the province of Newfoundland and Labrador is genetically isolated. This isolation is evidenced by an overabundance of several monogenic disorders. The Newfoundland population, like that of other isolates, is now the focus of interest for identification of genes implicated in common diseases. However, the utility of such populations for this purpose remains unproven. In this paper, we review the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Celiac Disease Research and Management
Share to Genetic Associations and Epidemiology
Share to Genomic variations and chromosomal abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12915452
DOI: 10.1093/hmg/ddg257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Newfoundland population: a unique resource for genetic investigation of complex diseasesPMID 12915452Read ↗

Genetic structure of the Newfoundland and Labrador population: founder effects modulate variability.Semantic proximity Read ↗

Newfoundland and Labrador: A mosaic founder population of an Irish and British diaspora from 300 years agoSemantic proximity Read ↗

Mitogenomic and microsatellite variation in descendants of the founder population of Newfoundland: high genetic diversity in an historically isolated population.Semantic proximity Read ↗

Characterization of Y chromosome diversity in newfoundland and labrador: evidence for a structured founding population.Semantic proximity Read ↗

Genomic and genealogical investigation of the French Canadian founder population structure.Semantic proximity Read ↗

Clinical and genetic epidemiology of inherited renal disease in Newfoundland.Semantic proximity Read ↗

Human Genetics: Lessons from Quebec PopulationsSemantic proximity Read ↗

Genetic disease risks of under-represented founder populations in New York CitySemantic proximity Read ↗

Fragmentation of the Québec population genetic pool (Canada): evidence from the genetic contribution of founders per region in the 17th and 18th centuries.Semantic proximity Read ↗

Molecular genetics of achromatopsia in Newfoundland reveal genetic heterogeneity, founder effects and the first cases of Jalili syndrome in North America.Semantic proximity Read ↗

Isolated populations and complex disease gene identification.Semantic proximity Read ↗

Rare variants and founder effect in an understudied Quebec populationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.