Article
Genomic and genealogical investigation of the French Canadian founder population structure.
Human genetics - 1 May 2011
Roy-Gagnon Marie-Hélène, Moreau Claudia, Bherer Claude, St-Onge Pascal, Sinnett Daniel, Laprise Catherine, Vézina Hélène, Labuda Damian
Abstract excerpt
Characterizing the genetic structure of worldwide populations is important for understanding human history and is essential to the design and analysis of genetic epidemiological studies. In this study, we examined genetic structure and distant relatedness and their effect on the extent of linkage disequilibrium (LD) and homozygosity in the founder population of Quebec (Canada). In the French Canadian founder...
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