Article

Rare variants and founder effect in an understudied Quebec population

2025-01-23

Abstract excerpt

Founder events influenced the genetic diversity within the Quebec province, increasing the frequency of certain rare pathogenic variants in regional populations. Some regions such as Beauce remain understudied despite evidence of a regional founder effect. Leveraging extensive genealogical data, we found a specific regional structure emerging in Beauce following the initial settlement, with a gradual increase of t...

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Literature Corpus work: 7b4305fa-3ee5-55c2-bcc4-cf3e054a9ac2
DOI: 10.1101/2025.01.21.25320907

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