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Article

Altered DNA Methylation Profile in Idiopathic Pulmonary Fibrosis

15 Jun 2012

Abstract excerpt

RATIONALE: DNA methylation is an important epigenetic mechanism, which often occurs in response to environmental stimuli and is crucial in regulating gene expression. It is likely that epigenetic alterations contribute to pathogenesis in idiopathic pulmonary fibrosis (IPF). OBJECTIVES: To determine the DNA methylation changes in IPF and their effects on gene expression. METHODS: Total DNA methylation and DNA...

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Share to Epigenetics and DNA Methylation
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 22700861
DOI: 10.1164/rccm.201201-0077oc

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