Article
Polymorphisms in folate-metabolizing genes and risk of non-Hodgkin's lymphoma.
Leukemia research - 1 Apr 2011
Weiner Alexandra S, Beresina Olga V, Voronina Elena N, Voropaeva Elena N, Boyarskih Uljana A, Pospelova Tatiana I, Filipenko Maxim L
Abstract excerpt
We investigated the role of single nucleotide polymorphisms (SNPs) in the folate-metabolizing genes MTHFR, MTR, MTRR, MTHFD, CBS and SHMT in regulating genetic susceptibility to Non-Hodgkin's lymphoma (NHL). We determined the allele and genotype frequencies in the case group (146 patients with NHL) and the control group (540 blood donors). A significant association with NHL was observed only for MTHFD1 G1958A...
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