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Article

The Bcl-2 Family in Host-Virus Interactions

6 Oct 2017

Abstract excerpt

Members of the B cell lymphoma-2 (Bcl-2) family are pivotal arbiters of mitochondrially mediated apoptosis, a process of fundamental importance during tissue development, homeostasis, and disease. At the structural and mechanistic level, the mammalian members of the Bcl-2 family are increasingly well understood, with their interplay ultimately deciding the fate of a cell. Dysregulation of Bcl-2-mediated apoptosis...

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PMID: 28984827
DOI: 10.3390/v9100290

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