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Article

Bcl-2 family proteins: master regulators of cell survival

1 Aug 2016

Abstract excerpt

The most prominent function of proteins of the Bcl-2 family is regulation of the initiation of intrinsic (mitochondrial) pathways of apoptosis. However, recent research has revealed that in addition to regulation of mitochondrial apoptosis, proteins of the Bcl-2 family play important roles in regulating other cellular pathways with a strong impact on cell survival like autophagy, endoplasmic reticulum (ER) stress...

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PMID: 27505095
DOI: 10.1515/bmc-2016-0015

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