Article
Association of AGTR1 Promoter Methylation Levels with Essential Hypertension Risk: A Matched Case-Control Study.
Cytogenetic and genome research - 1 Jan 2015
Fan Rui, Mao Shuqi, Zhong Fade, Gong Minli, Yin Fengying, Hao Lingmei, Zhang Lina
Abstract excerpt
UNLABELLED: The purpose of the present study was to investigate whether methylation of the angiotensin II type 1 receptor (AGTR1) promoter contributed to the risk of essential hypertension (EH). A total of 96 EH cases and 96 gender- and age-matched healthy controls were recruited. Methylation of 8 CpG dinucleotides (CpG1-8) in the AGTR1 promoter was examined using the bisulphite pyrosequencing technology. Three...
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