Article
DNA Methylation and Blood Pressure Phenotypes: A Review of the Literature.
American journal of hypertension - 2 Apr 2021
Irvin Marguerite R, Jones Alana C, Claas Steven A, Arnett Donna K
Abstract excerpt
Genetic studies of DNA have been unable to explain a significant portion of the variance of the estimated heritability of blood pressure (BP). Epigenetic mechanisms, particularly DNA methylation, have helped explain additional biological processes linked to BP phenotypes and diseases. Candidate gene methylation studies and genome-wide methylation studies of BP have highlighted impactful cytosine-phosphate-guanine...
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