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Article

Hypomethylation of the Toll-like receptor-2 gene increases the risk of essential hypertension.

Molecular medicine reports - 1 Jul 2017

Mao Shuqi, Gu Tianlun, Zhong Fade, Fan Rui, Zhu Fubao, Ren Peipei, Yin Fengying, Zhang Lina

Abstract excerpt

Studies on the etiology of essential hypertension (EH) have demonstrated that chronic inflammation contributes to the onset and development of elevated blood pressure. Toll‑like receptors (TLRs), important immune receptors, serve a role in chronic inflammation and are associated with EH. In the present study, 96 patients with EH, and 96 age‑ and sex‑matched healthy controls were recruited, and eight...

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Source

Identifiers

PMID: 28560381
DOI: 10.3892/mmr.2017.6653

Genes

TLR2

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