Article
Association of SCNN1B promoter methylation with essential hypertension.
Molecular medicine reports - 1 Dec 2016
Zhong Qilong, Liu Chunyan, Fan Rui, Duan Shiwei, Xu Xuting, Zhao Jinshun, Mao Shuqi, Zhu Wen, Hao Lingmei, Yin Fengying, Zhang Lina
Abstract excerpt
The amiloride-sensitive sodium channel beta subunit (SCNN1B) gene encodes the beta subunit of the epithelial sodium channel, which is involved in blood pressure homeostasis. The aim of the present study was to investigate the association between SCNN1B gene promoter methylation and essential hypertension (EH), and to explore whether SCNN1B methylation was altered by antihypertensive therapy. The present study...
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