Article
Angiotensin II type 2 receptor gene polymorphisms and essential hypertension.
Acta pharmacologica Sinica - 1 Nov 2003
Zhang Yi, Zhang Kui-Xing, Wang Gu-Liang, Huang Wei, Zhu Ding-Liang
Abstract excerpt
AIM: To identify the genetic variants of angiotensin II type 2 receptor (AT2R) gene in a Chinese population and to determine whether the AT2R gene polymorphisms are associated with essential hypertension (EH). METHODS: The detection of single nucleotide polymorphisms (SNPs) was performed in 19 subjects by a direct DNA sequencing. Two hundred fifty patients with EH and 250 nomortensive controls were included in...
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