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Article

Preliminary analysis of the association between methylation of the ACE2 promoter and essential hypertension.

Molecular medicine reports - 1 Jun 2017

Fan Rui, Mao Shu-Qi, Gu Tian-Lun, Zhong Fa-De, Gong Min-Li, Hao Ling-Mei, Yin Feng-Ying, Dong Chang-Zheng, Zhang Li-Na

Abstract excerpt

The aim of the present study was to investigate whether methylation of the angiotensin I converting enzyme 2 (ACE2) promoter increases the risk of essential hypertension (EH). A total of 96 patients with EH were recruited and 96 sex‑ and age‑matched healthy controls. Methylation of 5 CpG dinucleotides in the ACE2 promoter was quantified using bisulfite pyrosequencing. Logistic regression and multiple linear...

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Angiotensin-Converting Enzyme 2
Biomarkers
CpG Islands
DNA Methylation
Essential Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptidyl-Dipeptidase A

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Identifiers

PMID: 28440441
DOI: 10.3892/mmr.2017.6460

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ACE2

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