Article
Comparison Between Real-Time PCR and Pyrosequencing for Detection of BRAF V600E Mutation in Thyroid Fine-Needle Aspirates.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2000
Kim Wook Youn, Kim Hyunkyung, Hwang Tae Sook, Oh Seo Young
Abstract excerpt
The BRAF V600E mutation test has proven diagnostic value in thyroid fine-needle aspiration. The real-time polymerase chain reaction (RT-PCR) has recently been introduced as a new method for BRAF mutation detection. We performed BRAF V600E detection in 126 cases of thyroid fine-needle aspiration, using RT-PCR and pyrosequencing. BRAF V600E mutation was detected in 78 (61.9%) of 126 cases by RT-PCR and in 74...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
