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Article

Pyrosequencing cut-off value identifying BRAFV600E mutation in fine needle aspiration samples of thyroid nodules.

Clinical endocrinology - 1 Oct 2011

Yeo Min-Kyung, Liang Zhe Long, Oh Taejeong, Moon Youngho, An Sungwhan, Kim Min Kyeong, Kim Koon Soon, Shong Minho, Kim Jin-Man, Jo Young Suk

Abstract excerpt

CONTEXT: Recently, tremendous efforts have been made towards the development of sensitive techniques to detect the BRAF(V600E) mutation in fine needle aspiration biopsy (FNAB) samples. However, newly developed quantitative and semi-quantitative methods, such as dual-priming oligonucleotide (DPO)-based multiplex polymerase chain reaction (PCR), have the potential to generate false-positive (FP) results....

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Share to bioluminescence and chemiluminescence research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Identifiers

PMID: 21609347
DOI: 10.1111/j.1365-2265.2011.04115.x

Genes

BRAF

Variants

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