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Article

Detection of RAS mutation by pyrosequencing in thyroid cytology samples.

International journal of surgery (London, England) - 1 Jan 2014

Guerra Anna, Carrano Mario, Angrisani Elisabetta, Puzziello Alessandro, Izzo Giulia, Di Crescenzo Vincenzo, Vatrella Alessandro, Vitale Mario

Abstract excerpt

INTRODUCTION: Fine-needle aspiration cytology (FNAC) is the primary means to distinguish benign from malignant thyroid nodules. However, adjunctive diagnostic tests are needed as 20-40% of FNAC are inconclusive. RAS mutations have been described in differentiated thyroid cancer and they could be used as tumor markers. However, their prevalence varies widely among studies, probably as a result of the detection...

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Source

Identifiers

PMID: 24866065
DOI: 10.1016/j.ijsu.2014.05.045

Genes

KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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