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Article

A testing algorithm for detection of the B-type Raf kinase V600E mutation in papillary thyroid carcinoma.

Human pathology - 1 Jul 2014

Kim Yon Hee, Choi Sung-Eun, Yoon Sun Och, Hong Soon Won

Abstract excerpt

The B-type Raf kinase (BRAF) V600E mutation is a useful diagnostic marker for papillary thyroid carcinoma (PTC). We developed a testing algorithm for the BRAF mutation using BRAF immunohistochemistry (IHC) in PTC. Formalin-fixed, paraffin-embedded PTC tissues from 91 patients were immunostained with a BRAF V600E mutation-specific antibody. The immunostaining results were interpreted semiquantitatively by adding...

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Identifiers

PMID: 24745617
DOI: 10.1016/j.humpath.2014.02.025

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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