A testing algorithm for detection of the B-type Raf kinase V600E mutation in papillary thyroid carcinoma.

doi:10.1016/j.humpath.2014.02.025

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Article

A testing algorithm for detection of the B-type Raf kinase V600E mutation in papillary thyroid carcinoma.

Human pathology - 1 Jul 2014

Kim Yon Hee, Choi Sung-Eun, Yoon Sun Och, Hong Soon Won

Abstract excerpt

The B-type Raf kinase (BRAF) V600E mutation is a useful diagnostic marker for papillary thyroid carcinoma (PTC). We developed a testing algorithm for the BRAF mutation using BRAF immunohistochemistry (IHC) in PTC. Formalin-fixed, paraffin-embedded PTC tissues from 91 patients were immunostained w...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Algorithms
Carcinoma, Papillary
Humans
Immunohistochemistry
Middle Aged
Mutation
Proto-Oncogene Proteins B-raf
Thyroid Neoplasms
Young Adult

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