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Article

Mutant SOD1 mediated pathogenesis of Amyotrophic Lateral Sclerosis.

Gene - 15 Feb 2016

Kaur Simran J, McKeown Stephanie R, Rashid Shazia

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neural disorder that causes death of the motor neurons in the brain and spinal cord; this affects the voluntary muscles and gradually leads to paralysis of the whole body. Most ALS cases are sporadic, though about 5-10% are familial. ALS is caused by multiple factors including mutation in any one of a number of specific genes, one of the most frequently affected is...

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Source

Identifiers

PMID: 26657039
DOI: 10.1016/j.gene.2015.11.049

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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