Amyotrophic lateral sclerosis associated with mutations in superoxide dismutase: a putative mechanism of degeneration.

doi:10.1016/s0165-0173(98)00049-6

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Article

Amyotrophic lateral sclerosis associated with mutations in superoxide dismutase: a putative mechanism of degeneration.

Brain research. Brain research reviews - 1 Jan 1999

Morrison B M, Morrison J H

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a devastating neurologic disease that rapidly progresses from mild motor symptoms to severe motor paralysis and premature death. Until recently, there were few substantive studies conducted on the pathogenesis of the disease. With the genetic linkage of muta...

Topics

Amyotrophic Lateral Sclerosis
Animals
Humans
Mice
Mice, Transgenic
Mutation
Nerve Degeneration
Superoxide Dismutase

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