Article
Survivin polymorphism is associated with disease activity in rheumatoid arthritis patients.
Pharmacogenomics - 1 Jan 2016
Jenko Barbara, Praprotnik Sonja, Čučnik Saša, Rotar Žiga, Tomšič Matija, Dolžan Vita
Abstract excerpt
AIM: Survivin expression was associated with unfavorable and erosive course of rheumatoid arthritis (RA). This is the first study investigating association between BIRC5 polymorphisms, survivin plasma levels and disease activity in RA. PATIENTS & METHODS: A testing group of 123 and validation group of 150 RA patients initially treated with methotrexate monotherapy were genotyped for three BIRC5 promoter...
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