Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of survivin promoter polymorphisms with inflammatory bowel disease and response to antitumor necrosis factor therapy.

Genetic testing and molecular biomarkers - 1 Jun 2015

Rapti Emmanouela, Gazouli Maria, Legaki Evangelia, Karamanolis George, Thomas Diamantis, Marinos Evangelos, Papaconstantinou Ioannis

Abstract excerpt

BACKGROUND/AIM: Recent evidence suggests that survivin, a member of the inhibitors of apoptosis family that prevents cell death and regulates cell division is implicated in the pathogenesis of inflammatory bowel disease (IBD). The aim of the study was to identify a possible association between individual genetic variation, IBD susceptibility, and response to infliximab (IFX). MATERIAL AND METHODS: The expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Inflammatory Bowel Diseases

Share to Infliximab

Share to Inhibitor of Apoptosis Proteins

Share to Promoter Regions, Genetic

Share to Survivin

Source

Identifiers

PMID: 25918954
DOI: 10.1089/gtmb.2015.0036

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of survivin promoter polymorphisms with inflammatory bowel disease and response to antitumor necrosis factor therapy.PMID 25918954Read ↗

Association between survivin gene polymorphisms and the susceptibility to colon cancer development in the Turkish population.Semantic proximity Read ↗

Survivin -31G/C promoter polymorphism and sporadic colorectal cancer.Semantic proximity Read ↗

Survivin polymorphism is associated with disease activity in rheumatoid arthritis patients.Semantic proximity Read ↗

Evaluation of tumor necrosis factor (TNF)-α mRNA expression level and the rs1799964 polymorphism of the TNF-α gene in peripheral mononuclear cells of patients with inflammatory bowel diseasesSemantic proximity Read ↗

The survivin -31 snp in human colorectal cancer correlates with survivin splice variant expression and improved overall survival.Semantic proximity Read ↗

The survivin -31 snp in human colorectal cancer correlates with survivin splice variant expression and improved overall survival.Semantic proximity Read ↗

Genetic polymorphisms of tumour necrosis factor alpha (TNF-α) promoter gene and response to TNF-α inhibitors in Spanish patients with inflammatory bowel disease.Semantic proximity Read ↗

Evaluation of immunohistochemical expression of survivin and its correlation with -31G/C gene polymorphism in colorectal cancer.Semantic proximity Read ↗

Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk.Semantic proximity Read ↗

Association between survivin -31G > C promoter polymorphism and cancer risk: a meta-analysis.Semantic proximity Read ↗

Survivin -31G>C polymorphism and gastrointestinal tract cancer risk: a meta-analysis.Semantic proximity Read ↗

The association between the survivin -31G/C promoter polymorphism and hepatocellular carcinoma risk in a Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.