Article
BIRC5 promoter SNPs do not affect nuclear survivin expression and survival of malignant pleural mesothelioma patients.
Journal of cancer research and clinical oncology - 1 Nov 2011
Hmeljak Julija, Erčulj Nina, Dolžan Vita, Kern Izidor, Cör Andrej
Abstract excerpt
PURPOSE: Malignant pleural mesothelioma is an incurable, asbestos-associated cancer. Its incidence is rapidly increasing and survival remains short. Apoptosis deregulation is an important feature of cancer and survivin, a member of the inhibitor-of-apoptosis-protein family encoded by the BIRC5 gene, has been suggested to have a role in the development and progression of several cancers. Genetic variability, in...
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