Article
Survivin rs9904341 (G>C) polymorphism contributes to cancer risk: an updated meta-analysis of 26 studies.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2014
Xu Lei, Zhou Xin, Xu Lin, Yin Rong
Abstract excerpt
Survivin, a member of the inhibitor of apoptosis protein family, encoded by BIRC5, is involved in the regulation of apoptosis and in cell cycle control. Emerging evidences indicate that polymorphism in BIRC5 promoter (rs9904341) is associated with cancer risk, but the results of individually published studies are inconclusive. Thus, an updated meta-analysis was performed. PubMed was searched for all eligible...
Topics
- Apoptosis
- Asian People
- Genetic Predisposition to Disease
- Genotype
- Humans
- Inhibitor of Apoptosis Proteins
- Neoplasms
- Polymorphism, Single Nucleotide
