Article
Functional polymorphism -31C/G in the promoter of BIRC5 gene and risk of nasopharyngeal carcinoma among chinese.
PloS one - 3 Feb 2011
Ma Fuchao, Zhang Hongxing, Zhai Yun, Huang Wenfeng, Zhao Chang, Ou Shengqiu, Zhou Hong, Yuan Wenzhao, Wang Zhifu, Wang Hongxue, Yue Wei, Yu Lixia, Li Peiyao, Xia Xia, Cai Mi, Zhang Yang, Cui Ying, He Fuchu, Ma Yilong, Zhou Gangqiao
Abstract excerpt
BACKGROUND: Baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5, also called as survivin) is a member of the inhibitor of apoptosis protein (IAP) family, which plays an important role in the occurrence and progression of cancer. Recently, a polymorphism in the promoter of BIRC5, -31C/G (rs9904341), was shown to influence BIRC5 expression. METHODS: We examined whether the -31C/G was related to the risk...
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