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Article

Survivin a pivotal antiapoptotic protein in rheumatoid arthritis

6 May 2019

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune disease, pathologically characterized by lymphocyte infiltration of the synovial membrane that leads to chronic inflammation and progressive joint damage. RA develops as a result of increased cell infiltration and cell proliferation as well as impaired cell death. Activated cells in joints including lymphocytes and fibroblast-like synoviocytes (FLS) survive for a long...

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PMID: 31062383
DOI: 10.1002/jcp.28784

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