Article
Functional promoter -31G/C variant of Survivin gene predict prostate cancer susceptibility among Chinese: a case control study.
BMC cancer - 24 Jul 2013
Chen Jiawei, Cui Xinhai, Zhou Hai, Qin Chao, Cao Qiang, Ju Xiaobing, Li Pu, Cai Hongzhou, Zhu Jian, Meng Xiaoxin, Wang Meilin, Zhang Zhengdong, Shao Pengfei, Li Jie, Yin Changjun
Abstract excerpt
BACKGROUND: Abnormal expression of Baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5, also called as survivin), a novel member of the inhibitor of apoptosis protein (IAP) family, has implications in many types of cancer and is considered as a new therapeutic target. We suppose that genetic variant rs9904341 in the 5' UTR region of survivin gene may be associated with the development and progression of...
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