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Article

Investigating the linkage between disease-causing amino acid variants and their effect on protein stability and binding.

Proteins - 1 Feb 2016

Peng Yunhui, Alexov Emil

Abstract excerpt

Single amino acid variations (SAV) occurring in human population result in natural differences between individuals or cause diseases. It is well understood that the molecular effect of SAV can be manifested as changes of the wild type characteristics of the corresponding protein, among which are the protein stability and protein interactions. Typically the effect of SAV on protein stability and interactions was...

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Identifiers

PMID: 26650512
DOI: 10.1002/prot.24968
PMCID: PMC4955551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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