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Article

The effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on protein-protein interactions.

Journal of molecular biology - 1 Nov 2013

Yates Christopher M, Sternberg Michael J E

Abstract excerpt

Non-synonymous single nucleotide polymorphisms (nsSNPs) are single base changes leading to a change to the amino acid sequence of the encoded protein. Many of these variants are associated with disease, so nsSNPs have been well studied, with studies looking at the effects of nsSNPs on individual proteins, for example, on stability and enzyme active sites. In recent years, the impact of nsSNPs upon protein-protein...

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Identifiers

PMID: 23867278
DOI: 10.1016/j.jmb.2013.07.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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