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PI3K/Akt signaling pathway is involved in the neurotrophic effect of senegenin

7 Dec 2015

Abstract excerpt

Neurodegenerative diseases are frequently associated with the loss of synapses and neurons. Senegenin, extracted from the Chinese herb Polygala tenuifolia Willd, was previously found to promote neurite outgrowth and neuronal survival in primary cultured rat cortical neurons. The aim of the present study was to investigate the underlying mechanisms of senegenin-induced neurotrophic effects on rat cortical neurons....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26647727
DOI: 10.3892/mmr.2015.4652

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