Article

Paeoniflorin Ameliorates Cognitive Impairment in Parkinson’s Disease via JNK/p53 Signaling

2021-12-15

Abstract excerpt

Paeoniflorin (PF) has numerous benefits, including anti-inflammatory and anti-apoptosis effects. It also exhibits neuroprotective effects in Alzheimer’s disease (AD) via the ROS-JNK-p53 pathway. However, it is not clear if it has neuroprotective effects against cognitive impairment in Parkinson’s disease (PD). Through network pharmacology, we identified probable targets as well as signal pathways through which PF...

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Literature Corpus work: 70fddf66-62d8-57db-92b4-4c6dc0d050d9
DOI: 10.21203/rs.3.rs-1155409/v1

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