Baicalin Attenuated A β 1-42 ‐Induced Apoptosis in SH‐SY5Y Cells by Inhibiting the Ras‐ERK Signaling Pathway

Abstract excerpt

Alzheimer’s disease (AD) is a serious neurodegenerative disease. It is widely believed that the accumulation of amyloid beta (A β ) in neurons around neurofibrillary plaques is the main pathological characteristic of AD; however, the molecular mechanism underlying these pathological changes is not clear. Baicalin is a flavonoid extracted from the dry root of Scutellaria baicalensis Georgi . Studies have shown...

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