Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of gene polymorphims on the warfarin treatment at initial stage.

The pharmacogenomics journal - 1 Jan 2017

Liu J, Jiang H H, Wu D K, Zhou Y X, Ye H M, Li X, Luo Z Y, Guo Z, Zhang Y L, Wang Y C, Zhang W, Zhou H H, Wang L S

Abstract excerpt

The adverse reactions of warfarin that were found mainly occurred in the first month. This study was carried out to observe the effect of gene polymorphisms on the warfarin therapy at the initial stage. Four-hundred and sixty Chinese patients began warfarin treatment with daily 2.5 mg after heart valve replacement operations were enrolled. The daily international normalized ratio (INR) for anticoagulation were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P450 Family 4
Share to Drug Dosage Calculations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Monitoring

Share to Heart Valve Prosthesis Implantation

Share to International Normalized Ratio

Share to Orosomucoid

Share to Pharmacogenomic Testing

Share to Vitamin K Epoxide Reductases

Source

Identifiers

PMID: 26644206
DOI: 10.1038/tpj.2015.81

Genes

VKORC1
ORM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of gene polymorphims on the warfarin treatment at initial stage.PMID 26644206Read ↗

Integrated analysis of clinical and genetic factors on the interindividual variation of warfarin anticoagulation efficacy in clinical practice.Semantic proximity Read ↗

The influence of genetic polymorphisms and interacting drugs on initial response to warfarin in Chinese patients with heart valve replacement.Semantic proximity Read ↗

A retrospective cohort study of pharmacogenetics of warfarin dosing in Chinese Adults with nonvalvular atrial fibrillationSemantic proximity Read ↗

Pharmacogenetics of warfarin dosing in ChineseAdults with nonvalvular atrial fibrillationSemantic proximity Read ↗

[Effect of genetic variations on adjusting of warfarin dose].Semantic proximity Read ↗

Extremely low warfarin dose in patients with genotypes of CYP2C9*3/*3 and VKORC1-1639A/A.Semantic proximity Read ↗

[Impact of CYP2C9 and VKORC1 polymorphism on warfarin response during initiation of therapy].Semantic proximity Read ↗

Pharmacogenetics of warfarin dosing in Chinese Adults with nonvalvular atrial fibrillationSemantic proximity Read ↗

Effect of gene polymorphism on bleeding complications in Chinese Han patients taking warfarin.Semantic proximity Read ↗

Warfarin dosage response related pharmacogenetics in Chinese population.Semantic proximity Read ↗

Impact of VKORC1, CYP2C9, CYP1A2, UGT1A1, and GGCX polymorphisms on warfarin maintenance dose: Exploring a new algorithm in South Chinese patients accept mechanical heart valve replacement.Semantic proximity Read ↗

To establish a model for the prediction of initial standard and maintenance doses of warfarin for the Han Chinese population based on gene polymorphism: a multicenter study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.