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Article

The influence of genetic polymorphisms and interacting drugs on initial response to warfarin in Chinese patients with heart valve replacement.

European journal of clinical pharmacology - 1 Jun 2011

Zhong Shi-Long, Liu Yuan, Yu Xi-Yong, Xu Dan, Tan Hong-Hong, Lin Qiu-Xiong, Yang Min, Lao Hai-Yan, Lin Shu-Guang

Abstract excerpt

PURPOSE: Compared with genetic factors, drug interactions were largely unexplored in warfarin pharmacogenetic studies. This study sought to systematically investigate the effects of genetic polymorphisms of VKORC1, STX4A, CYP2C9, CYP3A4, and GGCX and interacting drugs on the initial responses to...

Read the complete abstract on PubMed

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Share to Anticoagulants
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Share to Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21318593
DOI: 10.1007/s00228-011-0995-6

Genes

VKORC1
GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21318593-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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