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Article

N-Acetyltransferase 2 Genotypes Are Associated With Diisocyanate-Induced Asthma.

Journal of occupational and environmental medicine - 1 Dec 2015

Yucesoy Berran, Kissling Grace E, Johnson Victor J, Lummus Zana L, Gautrin Denyse, Cartier André, Boulet Louis-Philippe, Sastre Joaquin, Quirce Santiago, Tarlo Susan M, Cruz Maria-Jesus, Munoz Xavier, Luster Michael I, Bernstein David I

Abstract excerpt

OBJECTIVE: To investigate whether genetic variants of N-acetyltransferase (NAT) genes are associated with diisocyanate asthma (DA). METHODS: The study population consisted of 354 diisocyanate-exposed workers. Genotyping was performed using a 5'-nuclease polymerase chain reaction assay. RESULTS: The NAT2 rs2410556 and NAT2 rs4271002 variants were significantly associated with DA in the univariate analysis. In the...

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Identifiers

PMID: 26641831
DOI: 10.1097/JOM.0000000000000561
PMCID: PMC5215051

Genes

NAT2
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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