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Article

Genetic Variants and Systemic Complement Activation Levels Are Associated With Serum Lipoprotein Levels in Age-Related Macular Degeneration.

Investigative ophthalmology & visual science - 1 Dec 2015

Paun Constantin C, Ersoy Lebriz, Schick Tina, Groenewoud Joannes M M, Lechanteur Yara T, Fauser Sascha, Hoyng Carel B, de Jong Eiko K, den Hollander Anneke I

Abstract excerpt

PURPOSE: Genetic variants in genes encoding components of lipid metabolism have been associated with AMD. The aims of this study were to evaluate the relation of these genetic variants with serum lipid levels in AMD in a large case-control cohort (n = 3070) and to test for correlations between lipids and complement activation. METHODS: Single nucleotide polymorphisms (SNPs) in eight lipid metabolism genes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26641553
DOI: 10.1167/iovs.15-17035

Genes

APOE
CETP
FADS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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