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Article

Complement Activation Levels Are Related to Disease Stage in AMD.

Investigative ophthalmology & visual science - 9 Mar 2020

Heesterbeek Thomas J, Lechanteur Yara T E, Lorés-Motta Laura, Schick Tina, Daha Mohamed R, Altay Lebriz, Liakopoulos Sandra, Smailhodzic Dzenita, den Hollander Anneke I, Hoyng Carel B, de Jong Eiko K, Klevering B Jeroen

Abstract excerpt

Purpose: To study the levels of complement activation in different disease stages of AMD and the influence of genetic polymorphisms in complement genes. Methods: We included 797 patients with AMD and 945 controls from the European Genetic Database. Patients were grouped into five AMD stages: early AMD, intermediate AMD, central geographic atrophy, active choroidal neovascularization or inactive choroidal...

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Identifiers

PMID: 32176267
DOI: 10.1167/iovs.61.3.18
PMCID: PMC7401663

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