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Article

Genetic association and causal relationship between multiple modifiable risk factors and autoimmune liver disease: a two-sample mendelian randomization study.

Journal of translational medicine - 4 May 2024

Gao Weize, Peng Chong, Wang Zhan, Li Yongxin, Liu Mingjun

Abstract excerpt

BACKGROUND: The intricate etiology of autoimmune liver disease (AILD) involves genetic, environmental, and other factors that yet to be completely elucidated. This study comprehensively assessed the causal association between genetically predicted modifiable risk factors and AILD by employing Mendelian randomization. METHODS: Genetic variants associated with 29 exposure factors were obtained from genome-wide...

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Identifiers

PMID: 38704596
DOI: 10.1186/s12967-024-05247-y
PMCID: PMC11070123

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