Article
Management of adult Ph-positive acute lymphoblastic leukemia.
Hematology. American Society of Hematology. Education Program - 1 Jan 2015
Chiaretti Sabina, Foà Robin
Abstract excerpt
Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) has been regarded for decades as the ALL subgroup with the worse outcome. It represents the most frequent genetic subtype of adult ALL, and increases progressively with age. The introduction of tyrosine kinase inhibitors (TKIs) has enabled to obtain complete hematologic remissions (CHRs) in virtually all patients, including the elderly, to improve...
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