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Article

Current challenges and opportunities in treating adult patients with Philadelphia-negative acute lymphoblastic leukaemia.

British journal of haematology - 1 Dec 2017

Wolach Ofir, Amitai Irina, DeAngelo Daniel J

Abstract excerpt

Significant advances have been made in recent years in the field of Philadelphia-negative acute lymphoblastic leukaemia (ALL). New insights into the biology and genetics of ALL as well as novel clinical observations and new drugs are changing the way we diagnose, risk-stratify and treat adult patients with ALL. New genetic subtypes and alterations refine risk stratification and uncover new actionable therapeutic...

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Identifiers

PMID: 29076138
DOI: 10.1111/bjh.14916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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