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Article

How has the management of Ph+ acute lymphoblastic leukemia (ALL) changed over the years.

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2000

Chiaretti Sabina, Foà Robin

Abstract excerpt

For decades, Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) has been considered the ALL subgroup with the worse outcome. It represents the most frequent genetic subtype of adult ALL and, in the elderly, it accounts for approximately 50% of cases. The introduction of tyrosine kinase inhibitors (TKIs) has led to obtain complete hematologic remissions (CHR) in virtually all patients, to improve...

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Source

Identifiers

PMID: 27795512
DOI: 10.11406/rinketsu.57.2038

Genes

SCT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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