Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus.

doi:10.1186/s13075-015-0857-1

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Article

Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus.

Arthritis research & therapy - 3 Dec 2015

Zhu Zhengwei, Liang Zhuoyuan, Liany Herty, Yang Chao, Wen Leilei, Lin Zhiming, Sheng Yujun, Lin Yan, Ye Lei, Cheng Yuyan, Chang Yan, Liu Lu, Yang Lulu, Shi Yinjuan, Shen Changbing, Zhou Fusheng, Zheng Xiaodong, Zhu Jun, Liang Bo, Ding Yantao, Zhou Yi, Yin Xianyong, Tang Huayang, Zuo Xianbo, Sun Liangdan, Bei Jin-Xin, Liu Jianjun, Yang Sen, Yang Wanling, Cui Yong, Zhang Xuejun

Abstract excerpt

INTRODUCTION: Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease affecting predominantly females. To discover additional genetic risk variants for SLE on the X chromosome, we performed a follow-up study of our previously published genome-wide association study (GWAS) data set in this study. METHODS: Twelve single nucleotide polymorphisms (SNPs) within novel or unpublished loci with...

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PMID: 26635088
DOI: 10.1186/s13075-015-0857-1
PMCID: PMC4669597

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