Article
Association of genetic variation on X chromosome with systemic lupus erythematosus in both Thai and Chinese populations.
Lupus science & medicine - 8 Mar 2024
Tangtanatakul Pattarin, Lei Yao, Jaiwan Krisana, Yang Wanling, Boonbangyang Manon, Kunhapan Punna, Sodsai Pimpayao, Mahasirimongkol Surakameth, Pisitkun Prapaporn, Yang Yi, Eu-Ahsunthornwattana Jakris, Aekplakorn Wichai, Jinawath Natini, Neelapaichit Nareemarn, Hirankarn Nattiya, Wang Yong-Fei
Abstract excerpt
OBJECTIVES: X chromosome has been considered as a risk factor for SLE, which is a prototype of autoimmune diseases with a significant sex difference (female:male ratio is around 9:1). Our study aimed at exploring the association of genetic variants in X chromosome and investigating the influence of trisomy X in the development of SLE. METHODS: X chromosome-wide association studies were conducted using data from...
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