Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infection

4 Dec 2015

Abstract excerpt

Flavivirus infection causes host cell death by initiation of an unfolded protein response (UPR). UPR is initiated following activation of three ER-membrane resident sensors, PERK, IRE1α and ATF6, which are otherwise kept inactive through association with the ER-chaperone GRP78. Activation precedes cellular and molecular changes that act to restore homeostasis but might eventually initiate apoptosis. These changes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to RNA regulation and disease
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26634309
DOI: 10.1038/srep17794

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infectionPMID 26634309Read ↗

The Role of Unfolded Protein Response in Coronavirus Infection and Its Implications for Drug DesignSemantic proximity Read ↗

Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulumSemantic proximity Read ↗

Coronavirus infection, ER stress, apoptosis and innate immunitySemantic proximity Read ↗

Stress responses in flavivirus-infected cells: activation of unfolded protein response and autophagySemantic proximity Read ↗

The UPRosome – decoding novel biological outputs of IRE1α functionSemantic proximity Read ↗

ATF4 Signaling in HIV Infection: Viral Subversion of a Stress Response Transcription FactorSemantic proximity Read ↗

BiP/GRP78 is a pro-viral factor for diverse dsDNA viruses that promotes the survival and proliferation of cells upon KSHV infectionSemantic proximity Read ↗

PERK Integrates Oncogenic Signaling and Cell Survival During Cancer DevelopmentSemantic proximity Read ↗

ATM-associated signalling triggers the unfolded protein response and cell death in response to stressSemantic proximity Read ↗

PERK-Olating Through Cancer: A Brew of Cellular DecisionsSemantic proximity Read ↗

Flavivirus Infection Activates the XBP1 Pathway of the Unfolded Protein Response To Cope with Endoplasmic Reticulum StressSemantic proximity Read ↗

Endoplasmic reticulum stress signaling: the microRNA connectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.