Article
No Evidence for Enrichment in Schizophrenia for Common Allelic Associations at Imprinted Loci.
PloS one - 1 Jan 2015
Escott-Price Valentina, Kirov George, Rees Elliott, Isles Anthony R, Owen Michael J, O'Donovan Michael C
Abstract excerpt
Most genetic studies assume that the function of a genetic variant is independent of the parent from which it is inherited, but this is not always true. The best known example of parent-of-origin effects arises with respect to alleles at imprinted loci. In classical imprinting, characteristically, either the maternal or paternal copy is expressed, but not both. Only alleles present in one of the parental copies...
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