Article
Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment.
Genes, brain, and behavior - 1 Apr 2014
Nudel R, Simpson N H, Baird G, O'Hare A, Conti-Ramsden G, Bolton P F, Hennessy E R, Ring S M, Davey Smith G, Francks C, Paracchini S, Monaco A P, Fisher S E, Newbury D F
Abstract excerpt
Specific language impairment (SLI) is a neurodevelopmental disorder that affects linguistic abilities when development is otherwise normal. We report the results of a genome-wide association study of SLI which included parent-of-origin effects and child genotype effects and used 278 families of language-impaired children. The child genotype effects analysis did not identify significant associations. We found...
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