Article
No evidence for a parent-of-origin effect detected in the pattern of inheritance of schizophrenia.
Biological psychiatry - 1 Oct 2000
DeLisi L E, Razi K, Stewart J, Relja M, Shields G, Smith A B, Wellman N, Larach V W, Loftus J, Vita A, Comazzi M, Crow T J
Abstract excerpt
BACKGROUND: Schizophrenia is a complex genetic disorder with no clear pattern of inheritance. Epigenetic modification of genes may thus play a role in its transmission. METHODS: In our study, 439 families with at least two ill siblings with schizophrenia (208 with unilineal transmission) were exa...
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