Article
Parent-of-origin effects in autism identified through genome-wide linkage analysis of 16,000 SNPs.
PloS one - 2 Sept 2010
Fradin Delphine, Cheslack-Postava Keely, Ladd-Acosta Christine, Newschaffer Craig, Chakravarti Aravinda, Arking Dan E, Feinberg Andrew, Fallin M Daniele
Abstract excerpt
BACKGROUND: Autism is a common heritable neurodevelopmental disorder with complex etiology. Several genome-wide linkage and association scans have been carried out to identify regions harboring genes related to autism or autism spectrum disorders, with mixed results. Given the overlap in autism features with genetic abnormalities known to be associated with imprinting, one possible reason for lack of consistency...
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